Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17891695 | 1.00 | KDM4C (0.43) | KDM4CKDM5BAKR1C3AKR1C2TOP2A | |
| SCHEMBL17891713 | 0.86 | MMP13 (0.47) | KDM4CKDM5BAKR1C3AKR1C2TOP2A | |
| SCHEMBL30589248 | 0.86 | MMP13 (0.47) | KDM4CKDM5BAKR1C3AKR1C2TOP2A | |
| SCHEMBL19383313 | 0.85 | AKR1C3 (0.48) | KDM4CKDM5BAKR1C3AKR1C2TOP2A | |
| SCHEMBL17898982 | 0.85 | TOP2A (0.42) | AKR1C3TOP2AMETALOX15L3MBTL1 | |
| SCHEMBL17891711 | 0.84 | KDM4C (0.42) | KDM4CKDM5BAKR1C3AKR1C2TOP2A | |
| SCHEMBL30589236 | 0.84 | KDM4C (0.42) | KDM4CKDM5BAKR1C3AKR1C2TOP2A | |
| SCHEMBL17891739 | 0.84 | KDM4C (0.42) | KDM4CKDM5BAKR1C3AKR1C2TOP2A | |
| SCHEMBL30589245 | 0.84 | KDM4C (0.42) | KDM4CKDM5BAKR1C3AKR1C2TOP2A | |
| SCHEMBL17898986 | 0.80 | CES2 (0.43) | AKR1C3TOP2AMETALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436445-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2023-09-06 | — | — | EP | disclosed |