Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.67 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.67 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25405433 | 1.00 | TAS1R3 (0.67) | TAS1R3TAS1R1TAS1R2KMT2AMEN1 | |
| SCHEMBL25405326 | 0.89 | TAS1R3 (0.60) | TAS1R3TAS1R1TAS1R2KMT2AMEN1 | |
| SCHEMBL31083790 | 0.89 | TAS1R3 (0.53) | TAS1R3TAS1R1TAS1R2KMT2AMEN1 | |
| SCHEMBL25405094 | 0.89 | TAS1R3 (0.53) | TAS1R3TAS1R1TAS1R2KMT2AMEN1 | |
| SCHEMBL25407518 | 0.87 | TAAR1 (0.65) | TAS1R3TAS1R1TAS1R2KMT2AMEN1 | |
| SCHEMBL30593250 | 0.87 | TAAR1 (0.65) | TAS1R3TAS1R1TAS1R2KMT2AMEN1 | |
| SCHEMBL25405686 | 0.87 | RAB9A (0.59) | TAS1R3TAS1R1TAS1R2KMT2AMEN1 | |
| SCHEMBL30593247 | 0.87 | RAB9A (0.59) | TAS1R3TAS1R1TAS1R2KMT2AMEN1 | |
| SCHEMBL31083758 | 0.86 | ROCK2 (0.54) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL25404576 | 0.86 | ROCK2 (0.54) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118742543-A | Dihydro isoquinoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-10-01 | — | — | CN | disclosed |
| CN-116789641-A | Dihydro isoquinoline compound and medical application thereof | 中国科学院上海药物研究所 | 2023-09-22 | — | — | CN | disclosed |