Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9903935 | 0.92 | CYP2D6 (0.60) | CYP2D6MAPTLMNAHSP90AA1MAPK14 | |
| SCHEMBL29500071 | 0.85 | MAPK13 (0.54) | CYP2D6HSP90AA1NOTUMMAPK14MAPK9 | |
| SCHEMBL2131373 | 0.85 | MAPK13 (0.54) | CYP2D6HSP90AA1NOTUMMAPK14MAPK9 | |
| Pyridine SCHEMBL28310314 | 0.84 | MAPK13 (0.50) | CYP2D6HSP90AA1NOTUMMAPK14MAPK9 | |
| SCHEMBL14425913 | 0.84 | CYP2D6 (0.46) | CYP2D6MAPTLMNANOTUMMAPK14 | |
| SCHEMBL2077041 | 0.83 | LMNA (0.56) | CYP2D6MAPTLMNANOTUMIDO1 | |
| Water SCHEMBL28117193 | 0.83 | MAPK13 (0.53) | CYP2D6HSP90AA1NOTUMMAPK14MAPK9 | |
| Hydrochloric Acid SCHEMBL11869763 | 0.83 | MAPK13 (0.53) | CYP2D6HSP90AA1NOTUMMAPK14MAPK9 | |
| SCHEMBL27926491 | 0.83 | MAPK13 (0.53) | CYP2D6HSP90AA1NOTUMMAPK14MAPK9 | |
| SCHEMBL30595872 | 0.83 | HSP90AA1 (0.52) | CYP2D6MAPTLMNAHSP90AA1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948497-A2 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND THEIR USE | Amgen inc. (US) | 1999-10-13 | — | — | EP | claimed |
| WO-1998024782-A2 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND THEIR USE | AMGEN INC. (US) | 1998-06-11 | — | — | WO | claimed |
| US-20230052191-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2023-02-16 | — | — | US | disclosed |
| CN-109970806-B | Organic metal iridium complex, preparation method thereof and application thereof in OLED | 中节能万润股份有限公司 | 2021-08-13 | — | — | CN | disclosed |
| EP-3828179-A1 | CYANOPYRROLIDINES AS DUB MODULATORS | Mission Therapeutics Limited (GB) | 2021-06-02 | — | — | EP | disclosed |
| US-10930853-B2 | Organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-02-23 | — | — | US | disclosed |
| US-20200369658-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2020-11-26 | — | — | US | disclosed |
| US-10774078-B2 | Compounds | MISSION THERAPEUTICS LTD (GB) | 2020-09-15 | — | — | US | disclosed |
| WO-2020165310-A1 | PYRIDINIUM COMPOUNDS AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-20 | — | — | WO | disclosed |
| WO-2020161162-A1 | HERBICIDAL PYRIDINIUM COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-13 | — | — | WO | disclosed |
| US-20190330202-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2019-10-31 | — | — | US | disclosed |
| US-20170155048-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-06-01 | — | — | US | disclosed |
| CN-105579445-A | Heterocyclic compound and organic light emitting device including the same | LG CHEMICAL LTD | 2016-05-11 | — | — | CN | disclosed |
| US-9059414-B2 | Phosphorescent organometallic iridium complex, light-emitting element, light-emitting device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-06-16 | — | — | US | disclosed |
| US-20150073144-A1 | Phosphorescent Organometallic Iridium Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2015-03-12 | — | — | US | disclosed |
| US-8889858-B2 | Phosphorescent organometallic iridium complex, light-emitting element, light-emitting device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-11-18 | — | — | US | disclosed |
| CN-103374043-A | Phosphorescent organometallic iridium complex, light-emitting element, light-emitting device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LAB | 2013-10-30 | — | — | CN | disclosed |
| US-20130281693-A1 | Phosphorescent Organometallic Iridium Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2013-10-24 | — | — | US | disclosed |
| US-20130004859-A1 | NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY USING THE SAME | LG ENERGY SOLUTION, LTD. (KR) | 2013-01-03 | — | — | US | disclosed |
| US-20130004859-A1 | NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY USING THE SAME | LG ENERGY SOLUTION, LTD. (KR) | 2013-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10774078-B2 | Compounds | UCHL1, UCHL3, UCHL5 | CYP2D6 2375/4885MAPT 2227/4885LMNA 4091/4885 |
| US-20200369658-A1 | NOVEL COMPOUNDS | UCHL1, UCHL3, UCHL5 | CYP2D6 2710/4885MAPT 2428/4885LMNA 4089/4885 |
| US-20190330202-A1 | NOVEL COMPOUNDS | UCHL1, UCHL3, UCHL5 | CYP2D6 2710/4885MAPT 2428/4885LMNA 4089/4885 |
| US-20230052191-A1 | NOVEL COMPOUNDS | UCHL1, UCHL3, UCHL5 | CYP2D6 2710/4885MAPT 2428/4885LMNA 4089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.