Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 1.00 |
| ▸ | USP2 | O75604 | 6/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 5/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 5/20 | 1.00 |
| ▸ | TP53 | P04637 | 5/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 4/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 4/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 3/20 | 1.00 |
| ▸ | THPO | P40225 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | KCNK2 | O95069 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 8/20 | 0.98 |
| ▸ | MEN1 | O00255 | 7/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.98 |
| ▸ | RAD52 | P43351 | 3/20 | 0.98 |
| ▸ | GMNN | O75496 | 3/20 | 0.98 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.98 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.98 |
| ▸ | HTR1A | P08908 | 4/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Z-Flupentixol SCHEMBL34200 | 1.00 | CYP3A4 (1.00) | CYP3A4USP2SIGMAR1CYP2D6MAPK1 | |
| E-Flupentixol SCHEMBL145726 | 1.00 | CYP3A4 (1.00) | CYP3A4USP2SIGMAR1CYP2D6MAPK1 | |
| E-Flupentixol SCHEMBL29598791 | 1.00 | CYP3A4 (1.00) | CYP3A4USP2SIGMAR1CYP2D6MAPK1 | |
| Z-Flupentixol SCHEMBL29361845 | 1.00 | CYP3A4 (1.00) | CYP3A4USP2SIGMAR1CYP2D6MAPK1 | |
| E-Flupentixol SCHEMBL414352 | 1.00 | CYP3A4 (1.00) | CYP3A4USP2SIGMAR1CYP2D6MAPK1 | |
| Z-Flupentixol SCHEMBL29620416 | 1.00 | CYP3A4 (1.00) | CYP3A4USP2SIGMAR1CYP2D6MAPK1 | |
| E-Flupentixol SCHEMBL11427109 | 0.99 | LMNA (1.00) | CYP3A4USP2SIGMAR1CYP2D6MAPK1 | |
| Z-Flupentixol SCHEMBL719323 | 0.99 | LMNA (1.00) | CYP3A4USP2SIGMAR1CYP2D6MAPK1 | |
| E-Flupentixol SCHEMBL1230220 | 0.99 | LMNA (1.00) | CYP3A4USP2SIGMAR1CYP2D6MAPK1 | |
| Z-Flupentixol SCHEMBL1153162 | 0.99 | LMNA (1.00) | CYP3A4USP2SIGMAR1CYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116804000-A | Specific palmitoyl transferase inhibitor and application thereof | 苏州大学 | 2023-09-26 | — | — | CN | claimed |
| CN-116804000-A | Specific palmitoyl transferase inhibitor and application thereof | 苏州大学 | 2023-09-26 | — | — | CN | disclosed |