Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | CASP3 | P42574 | 4/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.53 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28242727 | 0.89 | ESR2 (0.66) | RXFP1ESR2NPC1MAPTMEN1 | |
| SCHEMBL3716990 | 0.82 | RXFP1 (0.62) | RXFP1ESR2NPC1MAPTRAB9A | |
| SCHEMBL13996093 | 0.80 | NPC1 (0.63) | RXFP1NPC1MAPTRAB9ACASP3 | |
| SCHEMBL765406 | 0.79 | RXFP1 (0.58) | RXFP1NPC1KMT2ARAB9ACASP3 | |
| SCHEMBL5992639 | 0.79 | RXFP1 (0.58) | RXFP1NPC1MAPTRAB9ACASP3 | |
| SCHEMBL2021796 | 0.78 | RXFP1 (0.57) | RXFP1NPC1MAPTRAB9ACASP3 | |
| SCHEMBL10462626 | 0.78 | NPC1 (0.53) | RXFP1ESR2NPC1MAPTMEN1 | |
| SCHEMBL1551351 | 0.78 | RXFP1 (0.57) | RXFP1NPC1MAPTMEN1KMT2A | |
| SCHEMBL2699451 | 0.78 | RXFP1 (0.57) | RXFP1NPC1MAPTFYNRAB9A | |
| SCHEMBL8019903 | 0.77 | CASP3 (0.64) | RXFP1NPC1MAPTFYNRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479873-B2 | Metal complexes | UDC Ireland (IE) | 2025-11-25 | — | — | US | disclosed |
| US-20230322826-A1 | METAL COMPLEXES | UDC IRELAND LIMITED (IE) | 2023-10-12 | — | — | US | disclosed |
| US-11713332-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2023-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12479873-B2 | Metal complexes | AP1M1, SOD1, AP3M1 | RXFP1 4879/4885ESR2 1323/4885NPC1 3533/4885 |
| US-11713332-B2 | Metal complexes | AP1M1, SOD1, AP3M1 | RXFP1 4879/4885ESR2 1323/4885NPC1 3533/4885 |
| US-20230322826-A1 | METAL COMPLEXES | AP1M1, SOD1, AP3M1 | RXFP1 4879/4885ESR2 1323/4885NPC1 3533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.