Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19780624 | 1.00 | BACE1 (0.50) | BACE1HSD17B1HSD17B2CHEK2KDM1A | |
| SCHEMBL29028565 | 0.85 | KDM1A (0.51) | HSD17B1HSD17B2KDM1ATGFBR1ALDH1A1 | |
| Lithium SCHEMBL30459691 | 0.85 | KDM1A (0.51) | HSD17B1HSD17B2KDM1ATGFBR1ALDH1A1 | |
| SCHEMBL10756157 | 0.82 | POLB (0.54) | PDK2CYP2A6ALDH1A1HPGDLMNA | |
| SCHEMBL28597250 | 0.82 | MEN1 (0.55) | KDM1AALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL30834998 | 0.82 | MEN1 (0.55) | KDM1AALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL28600301 | 0.81 | KDM1A (0.51) | KDM1AALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL30835046 | 0.81 | KDM1A (0.51) | KDM1AALDH1A1HPGDHSD17B10LMNA | |
| Bromide SCHEMBL11334286 | 0.80 | POLB (0.52) | PDK2CYP2A6ALDH1A1HPGDLMNA | |
| SCHEMBL9974907 | 0.80 | LMNA (0.52) | TGFBR1CYP2A6ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479873-B2 | Metal complexes | UDC Ireland (IE) | 2025-11-25 | — | — | US | disclosed |
| US-20230322826-A1 | METAL COMPLEXES | UDC IRELAND LIMITED (IE) | 2023-10-12 | — | — | US | disclosed |
| US-11713332-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2023-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12479873-B2 | Metal complexes | AP1M1, SOD1, AP3M1 | BACE1 2970/4885HSD17B1 4416/4885HSD17B2 4256/4885 |
| US-11713332-B2 | Metal complexes | AP1M1, SOD1, AP3M1 | BACE1 2970/4885HSD17B1 4416/4885HSD17B2 4256/4885 |
| US-20230322826-A1 | METAL COMPLEXES | AP1M1, SOD1, AP3M1 | BACE1 2970/4885HSD17B1 4416/4885HSD17B2 4256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.