Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CCR1 | P32246 | 2/20 | 0.52 |
| ▸ | CCR5 | P51681 | 2/20 | 0.52 |
| ▸ | CCR8 | P51685 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | METAP1 | P53582 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 2/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9974919 | 0.98 | LMNA (0.50) | LMNAKDM4ECYP1A2CCR1CCR5 | |
| SCHEMBL14655918 | 0.96 | KDM4E (0.56) | LMNAKDM4ECYP1A2CCR1CCR5 | |
| SCHEMBL9974931 | 0.92 | KDM4E (0.52) | LMNAKDM4ECYP1A2CCR1CCR5 | |
| SCHEMBL9974904 | 0.91 | HPGDS (0.51) | LMNAKDM4ECYP1A2CCR1CCR5 | |
| SCHEMBL9974914 | 0.91 | TGFBR1 (0.46) | LMNAKDM4ECYP1A2CCR1CCR5 | |
| SCHEMBL9974911 | 0.91 | TGFBR1 (0.60) | LMNAKDM4ECYP1A2CCR1CCR5 | |
| SCHEMBL9974996 | 0.90 | KDM4E (0.50) | LMNAKDM4ECYP1A2CCR1CCR5 | |
| SCHEMBL9974951 | 0.90 | KDM4E (0.50) | LMNAKDM4ECYP1A2CCR1CCR5 | |
| SCHEMBL9974918 | 0.90 | KDM4E (0.50) | LMNAKDM4ECYP1A2CCR1CCR5 | |
| SCHEMBL9974934 | 0.89 | DHODH (0.48) | LMNAKDM4ECYP1A2CCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081541-A1 | 1, 2, 4, 5-SUBSTITUTED PHENYL DERIVATIVE, PRODUCTION METHOD FOR SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT | 東ソー株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |