SCHEMBL305975

SCHEMBL305975

CC1=NN(c2ccccc2)C(=O)C1N=Nc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 9/20 1.00
▸ ALDH1A1 P00352 6/20 1.00
▸ SMN1; SMN2 Q16637 4/20 1.00
▸ LMNA P02545 4/20 1.00
▸ MAPK1 P28482 4/20 1.00
▸ NPC1 O15118 3/20 1.00
▸ RAB9A P51151 3/20 1.00
▸ TDP1 Q9NUW8 2/20 1.00
▸ MEN1 O00255 9/20 0.82
▸ KMT2A Q03164 9/20 0.82
▸ POLB P06746 2/20 0.82
▸ KDM4E B2RXH2 1/20 0.82
▸ L3MBTL1 Q9Y468 1/20 0.82
▸ ATM Q13315 1/20 0.79
▸ CYP1A2 P05177 2/20 0.75
▸ GAA P10253 2/20 0.75
▸ CYP2D6 P10635 1/20 0.64
▸ CYP2C9 P11712 1/20 0.64
▸ CASP3 P42574 1/20 0.60
▸ SENP7 Q9BQF6 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL305974 1.00 MAPT (1.00) MAPTALDH1A1SMN1; SMN2LMNAMAPK1
SCHEMBL16645429 0.90 MAPT (0.81) MAPTALDH1A1SMN1; SMN2LMNAMAPK1
SCHEMBL342266 0.86 MAPT (0.75) MAPTALDH1A1SMN1; SMN2LMNAMAPK1
SCHEMBL31222678 0.86 MAPT (0.75) MAPTALDH1A1SMN1; SMN2LMNAMAPK1
SCHEMBL31152951 0.86 MEN1 (0.79) MAPTALDH1A1SMN1; SMN2LMNAMAPK1
SCHEMBL14255284 0.86 MEN1 (1.00) MAPTALDH1A1SMN1; SMN2LMNAMAPK1
SCHEMBL3833053 0.85 MAPT (0.73) MAPTALDH1A1SMN1; SMN2LMNAMAPK1
SCHEMBL8930539 0.85 MAPT (0.73) MAPTALDH1A1SMN1; SMN2LMNAMAPK1
SCHEMBL3833049 0.85 MAPT (0.73) MAPTALDH1A1SMN1; SMN2LMNAMAPK1
SCHEMBL3833055 0.85 MAPT (0.73) MAPTALDH1A1SMN1; SMN2LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12503528-B2 Thermoplastic moulding composition with improved weathering resistance RÖHM GMBH (DE) 2025-12-23 — — US claimed
US-12448520-B2 Process for colouring a thermoplastic polymer RÖHM GMBH (DE) 2025-10-21 — — US claimed
EP-3870631-B1 A POLYMER COMPOSITION SUITABLE FOR INJECTION MOULDING COMPRISING PARTICLES AND COLORANT, ITS METHOD OF PREPARATION AND ITS USE TRINSEO EUROPE GMBH (CH) 2025-02-12 — — EP claimed
EP-3870645-B1 A POLYMER COMPOSITION COMPRISING PARTICLES AND COLORANT, ITS METHOD OF PREPARATION AND ITS USE TRINSEO EUROPE GMBH (CH) 2024-12-11 — — EP claimed
EP-4165118-B1 THERMOPLASTIC MOULDING COMPOSITION WITH IMPROVED WEATHERING RESISTANCE ROEHM GMBH (DE) 2024-11-06 — — EP claimed
CN-118461161-A Spinning solution, preparation method of cotton composite yarn, cotton composite yarn and fabric 魏桥纺织股份有限公司 2024-08-09 — — CN claimed
US-20230212333-A1 THERMOPLASTIC MOULDING COMPOSITION WITH IMPROVED WEATHERING RESISTANCE RÖHM GMBH (DE) 2023-07-06 — — US claimed
US-20230203313-A1 PROCESS FOR COLOURING A THERMOPLASTIC POLYMER RÖHM GMBH (DE) 2023-06-29 — — US claimed
EP-4165123-A1 PROCESS FOR COLOURING A THERMOPLASTIC POLYMER Röhm GmbH (DE) 2023-04-19 — — EP claimed
EP-4165118-A1 THERMOPLASTIC MOULDING COMPOSITION WITH IMPROVED WEATHERING RESISTANCE Röhm GmbH (DE) 2023-04-19 — — EP claimed
CN-115715307-A Thermoplastic molding compositions with improved weathering resistance 罗姆化学有限责任公司 2023-02-24 — — CN claimed
CN-115698156-A Method for coloring thermoplastic polymers 罗姆化学有限责任公司 2023-02-03 — — CN claimed
US-20210380796-A1 A POLYMER COMPOSITION SUITABLE FOR INJECTION MOULDING COMPRISING PARTICLES AND COLORANT, ITS METHOD OF PREPARATION AND ITS USE ALTER DOMUS (US) LLC 2021-12-09 — — US claimed
US-20210371640-A1 A POLYMER COMPOSITION COMPRISING PARTICLES AND COLORANT, ITS METHOD OF PREPARATION AND ITS USE ALTER DOMUS (US) LLC 2021-12-02 — — US claimed
US-8092963-B2 Toner compositions XEROX CORPORATION (US) 2012-01-10 — — US claimed
EP-4713412-A1 HEAT TRANSFER FLUIDS FOR ELECTRIC VEHICLES Prestone Products Corporation (US) 2026-03-25 — — EP disclosed
US-12552957-B2 Industrial thermal inkjet inks VIDEOJET TECHNOLOGIES INC. (US) 2026-02-17 — — US disclosed
US-4492687-A Light-stable pesticidal compositions ROUSSEL UCLAF (FR) 1985-01-08 — — US disclosed
US-4440756-A Light-stable pesticidal compositions ROUSSEL UCLAF (FR) 1984-04-03 — — US disclosed
US-4440756-A Light-stable pesticidal compositions ROUSSEL UCLAF (FR) 1984-04-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552957-B2 Industrial thermal inkjet inks TBKBP1, ADH1A, ILK MAPT 197/4885ALDH1A1 106/4885SMN1; SMN2 3459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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