SCHEMBL3833049

SCHEMBL3833049

CC1=NN(c2ccccc2)C(=O)C1/N=N/c1cccc([N+](C)(C)C)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 10/20 0.73
▸ ALDH1A1 P00352 7/20 0.73
▸ NPC1 O15118 7/20 0.73
▸ RAB9A P51151 6/20 0.73
▸ SMN1; SMN2 Q16637 4/20 0.73
▸ LMNA P02545 3/20 0.73
▸ MAPK1 P28482 3/20 0.73
▸ TDP1 Q9NUW8 2/20 0.73
▸ MEN1 O00255 12/20 0.72
▸ KMT2A Q03164 12/20 0.72
▸ POLB P06746 3/20 0.63
▸ L3MBTL1 Q9Y468 2/20 0.63
▸ KDM4E B2RXH2 1/20 0.63
▸ ATM Q13315 1/20 0.60
▸ CYP1A2 P05177 2/20 0.59
▸ CYP2D6 P10635 1/20 0.59
▸ CYP2C9 P11712 1/20 0.59
▸ GAA P10253 1/20 0.58
▸ CASP3 P42574 1/20 0.46
▸ SENP7 Q9BQF6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3833055 1.00 MAPT (0.73) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL3833053 1.00 MAPT (0.73) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL2120386 0.99 MAPT (0.72) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL1086712 0.99 MAPT (0.72) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL2120385 0.99 MAPT (0.72) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL16645429 0.86 MAPT (0.81) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL305974 0.85 MAPT (1.00) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL305975 0.85 MAPT (1.00) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL15765846 0.82 MAPT (0.73) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL1689490 0.75 MAPT (0.70) MAPTALDH1A1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1740657-B1 CATIONIC NAPHTHYLDIAZO DYES AND AGENTS CONTAINING SAID DYES USED TO COLOUR KERATIN FIBRES WELLA AG (DE) 2007-09-12 — — EP claimed
EP-1424988-B1 LIGHTENING DYE WITH DIRECT-DYEING COLORANTS WELLA AG (DE) 2005-11-09 — — EP claimed
EP-0895472-B1 METHOD FOR DYEING KERATIN FIBRES WITH OXIDATION DYE PRECURSORS AND DIRECT POWDER DYES OREAL (FR) 2004-03-10 — — EP claimed
EP-0920856-B1 Process for direct dying of keratinous fibres in two steps with the help of direct basic dyes OREAL (FR) 2004-01-28 — — EP claimed
EP-0969798-B1 OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES AND DYEING METHOD USING SAID COMPOSITION OREAL (FR) 2003-07-23 — — EP claimed
EP-1047376-B1 KERATINOUS FIBRE DYEING COMPOSITION CONTAINING A LACCASE AND DYEING METHOD USING SAME OREAL (FR) 2001-05-23 — — EP claimed
EP-1047376-A1 KERATINOUS FIBRE DYEING COMPOSITION CONTAINING A LACCASE AND DYEING METHOD USING SAME L'OREAL (FR) 2000-11-02 — — EP claimed
EP-0998908-A2 Dyeing composition containing a cattonic and an oxidativ dye based an pyrazolo-(1,5)-pyramidine and dyeing process L'OREAL (FR) 2000-05-10 — — EP claimed
EP-0969798-A1 OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES AND DYEING METHOD USING SAID COMPOSITION L'OREAL (FR) 2000-01-12 — — EP claimed
WO-1999036034-A1 KERATINOUS FIBRE DYEING COMPOSITION CONTAINING A LACCASE AND DYEING METHOD USING SAME L'OREAL (FR) 1999-07-22 — — WO claimed
EP-0920856-A1 Process for direct dying of keratinous fibres in two steps with the help of direct basic dyes L'OREAL (FR) 1999-06-09 — — EP claimed
WO-1999017730-A1 OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES AND DYEING METHOD USING SAID COMPOSITION L'OREAL (FR) 1999-04-15 — — WO claimed
EP-0895472-A1 METHOD FOR DYEING KERATIN FIBRES WITH OXIDATION DYE PRECURSORS AND DIRECT POWDER DYES L'OREAL (FR) 1999-02-10 — — EP claimed
WO-1997039727-A1 METHOD FOR DYEING KERATIN FIBRES WITH OXIDATION DYE PRECURSORS AND DIRECT POWDER DYES L'OREAL (FR) 1997-10-30 — — WO claimed
US-20150101132-A1 CATIONIC DYE BEARING AN ANIONIC ORGANIC COUNTERION, DYE COMPOSITION COMPRISING THEM AND PROCESS FOR DYEING KERATIN USING THESE DYES L'OREAL (FR) 2015-04-16 — — US disclosed
EP-0971682-B2 DYEING COMPOSITION FOR KERATIN FIBRES AND DYEING METHOD USING SAME OREAL (FR) 2009-09-23 — — EP disclosed
EP-1352633-B1 Kit for dying keratinic fibers OREAL (FR) 2006-03-08 — — EP disclosed
WO-1999036034-A1 KERATINOUS FIBRE DYEING COMPOSITION CONTAINING A LACCASE AND DYEING METHOD USING SAME L'OREAL (FR) 1999-07-22 — — WO disclosed
EP-0920856-A1 Process for direct dying of keratinous fibres in two steps with the help of direct basic dyes L'OREAL (FR) 1999-06-09 — — EP disclosed
WO-1999020234-A1 DYEING COMPOSITION FOR KERATIN FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 1999-04-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150101132-A1 CATIONIC DYE BEARING AN ANIONIC ORGANIC COUNTERION, DYE COMPOSITION COMPRISING THEM AND PROCESS FOR DYEING KERATIN USING THESE DYES KRT18, COL14A1, COL1A1 MAPT 574/4885ALDH1A1 1317/4885NPC1 4790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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