Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 18/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30597964 | 0.80 | SMN1; SMN2 (0.49) | ABL1HPGD | |
| SCHEMBL30597949 | 0.79 | SLC5A1 (0.39) | SLC5A1ABL1HPGD | |
| SCHEMBL30009820 | 0.78 | HPGD (0.57) | ABL1HPGD | |
| SCHEMBL21961535 | 0.76 | CTSC (0.38) | ABL1HPGD | |
| SCHEMBL29697316 | 0.75 | ROCK2 (0.51) | ABL1HPGD | |
| SCHEMBL21874330 | 0.71 | APP (0.41) | HPGD | |
| SCHEMBL30369396 | 0.65 | NPC1 (0.60) | — | |
| SCHEMBL25041464 | 0.64 | CHRNB2 (0.37) | SLC5A1 | |
| SCHEMBL25042457 | 0.64 | CHRNB2 (0.37) | SLC5A1 | |
| SCHEMBL21961534 | 0.63 | GSK3B (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010080-B1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LTD (GB) | 2023-09-27 | — | — | EP | claimed |