Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GALR2 | O43603 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3543082 | 1.00 | POLB (0.37) | POLBLMNAGALR2SMN1; SMN2PDE4A | |
| SCHEMBL28471596 | 0.85 | PDE4A (0.40) | LMNASMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL15655816 | 0.81 | GSK3B (0.48) | LMNAKDM4EHPGDMEN1KMT2A | |
| SCHEMBL17305955 | 0.80 | PDPK1 (0.40) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15655815 | 0.78 | CDK2 (0.47) | POLBLMNAPDE4APDE4BPDE4C | |
| SCHEMBL3548733 | 0.77 | AXL (0.42) | PDPK1PARP1KDM4EMEN1KMT2A | |
| SCHEMBL9837779 | 0.77 | ALDH1A1 (0.45) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3544906 | 0.77 | GPR35 (0.39) | POLBSMN1; SMN2PDPK1PARP1KDM4E | |
| SCHEMBL30488581 | 0.77 | AXL (0.42) | PDPK1PARP1KDM4EMEN1KMT2A | |
| SCHEMBL15668241 | 0.77 | MEN1 (0.38) | PDE4BMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263952-A | Condensed-cyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-111836814-B | Condensed-cyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-10-20 | — | — | CN | disclosed |