Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759122 | 1.00 | ALDH1A1 (0.44) | ALDH1A1ATMHCAR2NAAAHPGD | |
| SCHEMBL8382643 | 0.84 | ALDH1A1 (0.42) | ALDH1A1ATMHCAR2NAAAHPGD | |
| SCHEMBL8382644 | 0.84 | ALDH1A1 (0.42) | ALDH1A1ATMHCAR2NAAAHPGD | |
| SCHEMBL3434106 | 0.83 | ALDH1A1 (0.41) | ALDH1A1ATMHCAR2NAAAHPGD | |
| SCHEMBL3616874 | 0.81 | ALDH1A1 (0.47) | ALDH1A1ATMHCAR2NAAAHPGD | |
| SCHEMBL25416858 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CHRNB2CHRNA4L3MBTL1SMN1; SMN2 | |
| SCHEMBL10912094 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CHRNB2CHRNA4L3MBTL1SMN1; SMN2 | |
| SCHEMBL7064837 | 0.81 | ALDH1A1 (0.42) | ALDH1A1ATMHCAR2NAAAHPGD | |
| SCHEMBL5077756 | 0.81 | ALDH1A1 (0.42) | ALDH1A1ATMHCAR2NAAAHPGD | |
| SCHEMBL7375873 | 0.80 | ALDH1A1 (0.39) | ALDH1A1ATMHCAR2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772177-B2 | BIR domain binding compounds | AEGERA THERAPEUTICS, INC. (CA) | 2010-08-10 | — | — | US | disclosed |
| WO-1999055688-A1 | SUBSTITUTED DIARYLALKYL AMIDES AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1999-11-04 | — | — | WO | disclosed |