Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3059935 | 0.81 | ALDH1A1 (0.44) | ALDH1A1ATMHPGDTSHRCHRNB2 | |
| SCHEMBL31269529 | 0.81 | ALDH1A1 (0.44) | ALDH1A1ATMHPGDTSHRCHRNB2 | |
| SCHEMBL1759122 | 0.81 | ALDH1A1 (0.44) | ALDH1A1ATMHPGDTSHRCHRNB2 | |
| SCHEMBL31269561 | 0.81 | ALDH1A1 (0.44) | ALDH1A1ATMHPGDTSHRCHRNB2 | |
| SCHEMBL8382644 | 0.80 | ALDH1A1 (0.42) | ALDH1A1ATMHPGDTSHRCHRNB2 | |
| SCHEMBL22689397 | 0.80 | ATM (0.44) | ALDH1A1ATMHPGDTSHRCHRNB2 | |
| SCHEMBL8382643 | 0.80 | ALDH1A1 (0.42) | ALDH1A1ATMHPGDTSHRCHRNB2 | |
| SCHEMBL3434106 | 0.79 | ALDH1A1 (0.41) | ALDH1A1ATMHPGDTSHRCHRNB2 | |
| SCHEMBL28494423 | 0.79 | ALDH1A1 (0.41) | ALDH1A1ATMHPGDTSHRCHRNB2 | |
| SCHEMBL1868925 | 0.78 | ALDH1A1 (0.48) | ALDH1A1ATMHPGDTSHRHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314247-B2 | Hydrazone derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-11-20 | — | — | US | disclosed |
| US-20100099662-A1 | HYDRAZONE DERIVATIVE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-04-22 | — | — | US | disclosed |
| EP-2105435-A1 | HYDRAZONE DERIVATIVE | Mitsubishi Tanabe Pharma Corporation (JP) | 2009-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099662-A1 | HYDRAZONE DERIVATIVE | GCK, GCKR, HK1 | ALDH1A1 1260/4885ATM 1159/4885HPGD 1353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.