Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.68 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | TYK2 | P29597 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224452 | 0.87 | RAB9A (0.67) | KDM4DKDM4CRAB9AABCB1NPC1 | |
| SCHEMBL28561950 | 0.82 | KDM4D (0.69) | KDM4DKDM4CRAB9AJAK2TYK2 | |
| SCHEMBL12320459 | 0.81 | KDM4D (0.68) | KDM4DKDM4CJAK2TYK2NAMPT | |
| SCHEMBL10644415 | 0.81 | HDAC2 (0.66) | KDM4DKDM4CRAB9AABCB1JAK2 | |
| SCHEMBL14439746 | 0.81 | KDM4D (0.68) | KDM4DKDM4CJAK2TYK2NAMPT | |
| SCHEMBL27598170 | 0.81 | KDM4D (0.68) | KDM4DKDM4CRAB9AABCB1JAK2 | |
| SCHEMBL996353 | 0.80 | KDM4D (0.62) | KDM4DKDM4CRAB9AABCB1NPC1 | |
| SCHEMBL6175231 | 0.79 | HDAC3 (0.73) | RAB9AABCB1NPC1HDAC1HDAC3 | |
| SCHEMBL2113824 | 0.79 | RAB9A (0.86) | RAB9ANPC1HDAC1HDAC3HDAC2 | |
| SCHEMBL29429740 | 0.79 | RAB9A (0.86) | RAB9ANPC1HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888101-A | Substituted isoxazoline derivatives | 巴斯夫欧洲公司 | 2023-10-13 | — | — | CN | disclosed |