Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.62 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | GSK3A | P49840 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | TYK2 | P29597 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694521 | 0.81 | ALDH1A1 (0.75) | MAPTHDAC1ALDH1A1RAB9ANPC1 | |
| SCHEMBL6170575 | 0.81 | POLB (0.67) | MAPTHDAC1HDAC8HDAC6GAA | |
| SCHEMBL30008296 | 0.81 | POLB (0.67) | MAPTHDAC1HDAC8HDAC6GAA | |
| SCHEMBL30599581 | 0.80 | KDM4D (0.68) | KDM4DKDM4CHDAC1HDAC8HDAC6 | |
| SCHEMBL896721 | 0.79 | GAA (0.49) | MAPTGSK3AGSK3BGAAALDH1A1 | |
| SCHEMBL23060423 | 0.78 | GAA (0.57) | MAPTGSK3AGSK3BGAAALDH1A1 | |
| SCHEMBL26624210 | 0.78 | GAA (0.57) | KDM4CMAPTGSK3AGSK3BGAA | |
| SCHEMBL28561950 | 0.78 | KDM4D (0.69) | KDM4DKDM4CHDAC1JAK2TYK2 | |
| SCHEMBL2224452 | 0.77 | RAB9A (0.67) | KDM4DKDM4CHDAC1GAAJAK2 | |
| SCHEMBL12320459 | 0.77 | KDM4D (0.68) | KDM4DKDM4CMAPTGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011514-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-01-27 | — | — | WO | disclosed |