Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13369863 | 1.00 | HSD11B1 (0.33) | HSD11B1ALDH1A1MAPTKDM4ERECQL | |
| SCHEMBL7051387 | 0.75 | SMN1; SMN2 (0.36) | HSD11B1 | |
| SCHEMBL25712668 | 0.74 | CYP1A2 (0.30) | — | |
| SCHEMBL5694385 | 0.74 | GRIN2D (0.31) | HSD11B1MAPTKDM4E | |
| SCHEMBL6217800 | 0.74 | CYP1A2 (0.33) | HSD11B1 | |
| SCHEMBL3516279 | 0.74 | MYC (0.30) | — | |
| SCHEMBL525836 | 0.72 | — | — | |
| SCHEMBL6025176 | 0.72 | ALDH1A1 (0.35) | ALDH1A1MAPTCA1CA2 | |
| SCHEMBL31496907 | 0.71 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL9687028 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677726-A | KRAS inhibitors | 百时美施贵宝公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-119630676-A | Pyrido [4,3-D ] pyrimidine derivatives as KRAS inhibitors | 百时美施贵宝公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-117881680-A | Tricyclic compounds as KRAS inhibitors | 因赛特公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117736222-A | MTA synergistic PRMT5 inhibitor compounds having tricyclic or tetracyclic ring structures | 烨辉医药科技(上海)有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117242079-A | KRAS G12D inhibitors and uses thereof | 苏州赞荣医药科技有限公司 | 2023-12-15 | — | — | CN | disclosed |