SCHEMBL31496907

SCHEMBL31496907

N#CN1CC(F)=Cc2cccnc21

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30600330 0.71 HSD11B1 (0.33) HSD11B1
SCHEMBL13369863 0.71 HSD11B1 (0.33) HSD11B1
SCHEMBL1702027 0.64 OTUD7B (0.35) HSD11B1
SCHEMBL28238908 0.59
SCHEMBL29417523 0.56 CYP1A2 (0.35)
SCHEMBL7170158 0.54 CA1 (0.39)
SCHEMBL178982 0.54 GAA (0.45)
SCHEMBL3295712 0.54 KDM4E (0.50) HSD11B1
SCHEMBL20242063 0.54 BDKRB1 (0.34)
SCHEMBL565864 0.54 KDM4E (0.61) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119585261-A PRMT5 inhibitor, preparation method and application thereof 上海艾力斯医药科技股份有限公司 2025-03-07 CN disclosed