Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 20/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31299185 | 0.86 | KIF18A (0.40) | KIF18A | |
| SCHEMBL30748599 | 0.85 | CDC7 (0.44) | KIF18A | |
| SCHEMBL26646192 | 0.85 | KIF18A (0.37) | KIF18A | |
| SCHEMBL22119526 | 0.83 | KIF18A (0.38) | KIF18A | |
| SCHEMBL25712739 | 0.82 | KIF18A (0.41) | KIF18A | |
| SCHEMBL29578579 | 0.81 | MEN1 (0.40) | KIF18A | |
| SCHEMBL22964565 | 0.81 | MEN1 (0.40) | KIF18A | |
| SCHEMBL31114174 | 0.80 | FFAR4 (0.52) | — | |
| SCHEMBL31299143 | 0.78 | KIF18A (0.43) | KIF18A | |
| SCHEMBL22148553 | 0.78 | HTR1A (0.38) | KIF18A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119156382-A | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2024-12-17 | — | — | CN | disclosed |
| WO-2024217348-A1 | KIF18A INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 南京同诺康医药科技有限公司 | 2024-10-24 | — | — | WO | disclosed |
| WO-2023217232-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |