SCHEMBL30601232

SCHEMBL30601232

N#CCc1ccccc1C1OCCO1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
FFAR1 O14842 2/20 0.32
KIF11 P52732 1/20 0.32
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP1B1 Q16678 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14948744 0.80 ALDH1A1 (0.40) ALDH1A1HPGDFFAR1KIF11CYP1A1
SCHEMBL9691788 0.79 ALDH1A1 (0.34) ALDH1A1HPGD
SCHEMBL11941061 0.76 CTSB (0.43)
SCHEMBL11081681 0.76 HTR2C (0.34) ALDH1A1
SCHEMBL954765 0.76 ALDH1A1 (0.42) ALDH1A1HPGDFFAR1CYP1A1CYP1A2
SCHEMBL11342700 0.76 APOBEC3G (0.38) ALDH1A1
SCHEMBL28432972 0.76 CYP2A13 (0.30)
SCHEMBL3727526 0.73 TSHR (0.36)
SCHEMBL8378247 0.73 TDP1 (0.34) KIF11
SCHEMBL20592264 0.72 TSHR (0.39) ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116514816-A Pyrimidinone pyrrole derivative and preparation method and medical application thereof 深圳信立泰药业股份有限公司 2023-08-01 CN disclosed