Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518709 | 0.86 | CYSLTR2 (0.37) | TDP1 | |
| SCHEMBL11342700 | 0.85 | APOBEC3G (0.38) | TDP1 | |
| SCHEMBL8938495 | 0.78 | HTR5A (0.32) | TDP1 | |
| SCHEMBL6156151 | 0.78 | APOBEC3G (0.35) | TDP1 | |
| SCHEMBL11081681 | 0.77 | HTR2C (0.34) | — | |
| SCHEMBL28432972 | 0.77 | CYP2A13 (0.30) | — | |
| SCHEMBL11941061 | 0.77 | CTSB (0.43) | TDP1 | |
| SCHEMBL14465955 | 0.76 | CYSLTR2 (0.36) | — | |
| SCHEMBL23662479 | 0.76 | KIF11 (0.38) | KIF11 | |
| SCHEMBL9520131 | 0.76 | CYSLTR2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883102-A | Pharmaceutically active compounds | ASTRA PHARMACEUTICALS LIMITED (GB) | 1999-03-16 | — | — | US | disclosed |
| EP-0858451-A1 | PHARMACEUTICALLY ACTIVE QUINAZOLINE COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997014686-A1 | PHARMACEUTICALLY ACTIVE QUINAZOLINE COMPOUNDS | ASTRA PHARMACEUTICALS LIMITED (GB) | 1997-04-24 | — | — | WO | disclosed |
| US-5236947-A | Side effect reduction | JOUVEINAL S.A. (FR) | 1993-08-17 | — | — | US | disclosed |