Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601283 | 0.88 | NPSR1 (0.39) | KDM4EALDH1A1HSD17B10NPSR1L3MBTL1 | |
| SCHEMBL30601230 | 0.77 | EPHX2 (0.43) | KDM4EALDH1A1HSD17B10L3MBTL1MEN1 | |
| SCHEMBL30601247 | 0.74 | EPHX2 (0.39) | KDM4EALDH1A1HSD17B10L3MBTL1MEN1 | |
| SCHEMBL30601276 | 0.71 | ALDH1A1 (0.39) | KDM4EALDH1A1HSD17B10NPSR1L3MBTL1 | |
| SCHEMBL30601236 | 0.69 | MAPT (0.48) | KDM4EALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL2526330 | 0.69 | HSD11B1 (0.40) | POLB | |
| SCHEMBL15908738 | 0.69 | TSHR (0.46) | KDM4EALDH1A1HSD17B10NPSR1MAPT | |
| SCHEMBL5337383 | 0.68 | SMN1; SMN2 (0.48) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL1654418 | 0.68 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10NPSR1L3MBTL1 | |
| SCHEMBL30601237 | 0.67 | KMT2A (0.38) | KDM4EALDH1A1HSD17B10L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514816-A | Pyrimidinone pyrrole derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-08-01 | — | — | CN | disclosed |