Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 9/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601308 | 1.00 | ALOX15 (0.38) | ALOX15LMNAUSP2MAPK1KDM4C | |
| SCHEMBL30601259 | 0.88 | KDM4E (0.39) | ALOX15LMNAALDH1A1KDM4ECYP1A2 | |
| SCHEMBL30601258 | 0.86 | GAA (0.39) | ALOX15LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL17782060 | 0.86 | GAA (0.39) | ALOX15LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL27224141 | 0.81 | ALDH1A1 (0.38) | ALOX15LMNAUSP2MAPK1KDM4C | |
| SCHEMBL27118027 | 0.81 | ALOX15 (0.42) | ALOX15LMNAUSP2ALDH1A1KDM4E | |
| SCHEMBL17782057 | 0.80 | ALOX15 (0.38) | ALOX15LMNAUSP2MAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27153929 | 0.80 | ALOX15 (0.41) | ALOX15LMNAUSP2ALDH1A1KDM4E | |
| SCHEMBL17782022 | 0.80 | ALOX15 (0.43) | ALOX15LMNAUSP2ALDH1A1KDM4E | |
| SCHEMBL27223533 | 0.79 | F2 (0.41) | ALOX15LMNAUSP2MAPK1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514816-A | Pyrimidinone pyrrole derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-08-01 | — | — | CN | disclosed |