Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SLC26A6 | Q9BXS9 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17782060 | 1.00 | GAA (0.39) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL30601308 | 0.86 | ALOX15 (0.38) | ALDH1A1ALOX15HPGDLMNAKDM4E | |
| SCHEMBL30601281 | 0.86 | ALOX15 (0.38) | ALDH1A1ALOX15HPGDLMNAKDM4E | |
| SCHEMBL30601271 | 0.86 | ASPH (0.44) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL30601259 | 0.85 | KDM4E (0.39) | GAAALDH1A1HSD17B10ALOX15HPGD | |
| SCHEMBL27224134 | 0.81 | ALOX15 (0.38) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL27223570 | 0.81 | ASPH (0.39) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL30749266 | 0.81 | ASPH (0.39) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL27223421 | 0.80 | ALDH1A1 (0.44) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL27224205 | 0.80 | ALDH1A1 (0.44) | GAAMGAMAMY1ASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514816-A | Pyrimidinone pyrrole derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-08-01 | — | — | CN | disclosed |