Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16316004 | 0.85 | ALDH1A1 (0.46) | ALDH1A1TDP1 | |
| SCHEMBL20490035 | 0.79 | ALDH1A1 (0.32) | ALDH1A1TDP1TSHR | |
| SCHEMBL1572826 | 0.79 | SMN1; SMN2 (0.42) | TDP1 | |
| SCHEMBL10189839 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRTRPA1 | |
| SCHEMBL19913381 | 0.77 | ALDH1A1 (0.31) | ALDH1A1TDP1TSHR | |
| SCHEMBL25867918 | 0.77 | TDP1 (0.48) | ALDH1A1TDP1 | |
| SCHEMBL10489371 | 0.77 | ECE1 (0.36) | ALDH1A1TDP1TSHR | |
| SCHEMBL17066267 | 0.77 | TDP1 (0.42) | ALDH1A1TDP1 | |
| SCHEMBL14342418 | 0.75 | ALDH1A1 (0.41) | ALDH1A1TDP1 | |
| SCHEMBL7940094 | 0.74 | ALDH1A1 (0.43) | ALDH1A1TDP1TSHRTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140336137-A1 | NOVEL NITROSO COMPOUNDS AS NITROXYL DONORS AND METHODS OF USE THEREOF | CARDIOXYL PHARMACEUTICALS, INC. | 2014-11-13 | — | — | US | disclosed |
| US-8299250-B2 | Chiral tridentate compounds, corresponding organometal complexes, method for preparing same and use of said compounds and complexes as ligands in asymmetrical catalysis | ECOLE NATIONALE SUPÉRIEURE DE CHIMIE DE RENNES (FR) | 2012-10-30 | — | — | US | disclosed |
| US-8299250-B2 | Chiral tridentate compounds, corresponding organometal complexes, method for preparing same and use of said compounds and complexes as ligands in asymmetrical catalysis | ECOLE NATIONALE SUPÉRIEURE DE CHIMIE DE RENNES (FR) | 2012-10-30 | — | — | US | disclosed |
| US-8299250-B2 | Chiral tridentate compounds, corresponding organometal complexes, method for preparing same and use of said compounds and complexes as ligands in asymmetrical catalysis | ECOLE NATIONALE SUPÉRIEURE DE CHIMIE DE RENNES (FR) | 2012-10-30 | — | — | US | disclosed |
| EP-2200986-B1 | Chiral tridentate compounds, corresponding organometal complexes, method for preparing same and use of said compounds and complexes as ligands in asymmetrical catalysis | ENSCR (FR) | 2012-08-08 | — | — | EP | disclosed |
| US-20100267956-A1 | CHIRAL TRIDENTATE COMPOUNDS, CORRESPONDING ORGANOMETAL COMPLEXES, METHOD FOR PREPARING SAME AND USE OF SAID COMPOUNDS AND COMPLEXES AS LIGANDS IN ASYMMETRICAL CATALYSIS | CNRS (CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE) (FR) | 2010-10-21 | — | — | US | disclosed |
| US-20100267956-A1 | CHIRAL TRIDENTATE COMPOUNDS, CORRESPONDING ORGANOMETAL COMPLEXES, METHOD FOR PREPARING SAME AND USE OF SAID COMPOUNDS AND COMPLEXES AS LIGANDS IN ASYMMETRICAL CATALYSIS | CNRS (CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE) (FR) | 2010-10-21 | — | — | US | disclosed |
| US-20100267956-A1 | CHIRAL TRIDENTATE COMPOUNDS, CORRESPONDING ORGANOMETAL COMPLEXES, METHOD FOR PREPARING SAME AND USE OF SAID COMPOUNDS AND COMPLEXES AS LIGANDS IN ASYMMETRICAL CATALYSIS | CNRS (CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE) (FR) | 2010-10-21 | — | — | US | disclosed |
| EP-2200986-A2 | CHIRAL TRIDENTATE COMPOUNDS, CORRESPONDING ORGANOMETAL COMPLEXES, METHOD FOR PREPARING SAME AND USE OF SAID COMPOUNDS AND COMPLEXES AS LIGANDS IN ASYMMETRICAL CATALYSIS | Ecole Nationale Superieure De Chimie De Rennes (FR) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009050284-A2 | CHIRAL TRIDENTATE COMPOUNDS, CORRESPONDING ORGANOMETAL COMPLEXES, METHOD FOR PREPARING SAME AND USE OF SAID COMPOUNDS AND COMPLEXES AS LIGANDS IN ASYMMETRICAL CATALYSIS | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES (FR) | 2009-04-23 | — | — | WO | disclosed |
| US-6380392-B1 | COMPLEXES | THE PENN STATE RESEARCH FOUNDATION | 2002-04-30 | — | — | US | disclosed |
| WO-2001000581-A1 | LIGANDS BASED ON CHIRAL 2-AMINO-2'-HYDROXY-1,1'-BINAPHTHYL AND RELATED FRAMEWORKS FOR ASYMMETRIC CATALYSIS | THE PENN STATE RESEARCH FOUNDATION (US) | 2001-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336137-A1 | NOVEL NITROSO COMPOUNDS AS NITROXYL DONORS AND METHODS OF USE THEREOF | NOXO1, TNNI3, HAO2 | ALDH1A1 624/4885TDP1 856/4885TSHR 3830/4885 |
| US-20100267956-A1 | CHIRAL TRIDENTATE COMPOUNDS, CORRESPONDING ORGANOMETAL COMPLEXES, METHOD FOR PREPARING SAME AND USE OF SAID COMPOUNDS AND COMPLEXES AS LIGANDS IN ASYMMETRICAL CATALYSIS | AOC1, C1R, AOC3 | ALDH1A1 1089/4885TDP1 2161/4885TSHR 686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.