Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30602784 | 0.80 | SMO (0.46) | PPARDPPARAMAOBCKS1BSKP2 | |
| SCHEMBL30602780 | 0.77 | CNR1 (0.44) | PPARDPPARAMAOBCKS1BSKP2 | |
| SCHEMBL30602790 | 0.73 | SCN9A (0.40) | PPARASCN9A | |
| SCHEMBL13202468 | 0.71 | SCN9A (0.49) | SCN9APTGS1PTGS2 | |
| SCHEMBL4794897 | 0.69 | SCN9A (0.48) | SCN9APTGS1PTGS2 | |
| SCHEMBL4793067 | 0.69 | PPARD (0.59) | PPARDPPARA | |
| SCHEMBL30602805 | 0.69 | PTGS2 (0.41) | SCN9APTGS1PTGS2 | |
| SCHEMBL4792820 | 0.69 | SCN9A (0.45) | SCN9APTGS1PTGS2 | |
| SCHEMBL29878600 | 0.68 | CASR (0.47) | PPARDPPARAMAOBAPPMAOA | |
| SCHEMBL31202813 | 0.68 | TEAD1 (0.40) | SCN9APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119095828-A | Indazole compound, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-12-06 | — | — | CN | disclosed |
| WO-2023186058-A1 | INDAZOLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2023-10-05 | — | — | WO | disclosed |