Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | CASR | P41180 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.33 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.33 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.33 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30602810 | 0.81 | SCN9A (0.40) | SCN9ACASRMAPTRAB9ACTDSP1 | |
| SCHEMBL31596223 | 0.80 | SCN9A (0.42) | SCN9AMAPTRAB9ACTDSP1L3MBTL1 | |
| SCHEMBL30602805 | 0.80 | PTGS2 (0.41) | SCN9ACNR1CYP2C9 | |
| SCHEMBL31202813 | 0.78 | TEAD1 (0.40) | SCN9AMAPTNR3C1CNR1TEAD1 | |
| SCHEMBL26108092 | 0.78 | TEAD1 (0.40) | SCN9AMAPTNR3C1CNR1TEAD1 | |
| SCHEMBL30602787 | 0.73 | PPARD (0.40) | SCN9APPARA | |
| SCHEMBL17195540 | 0.70 | NLRP3 (0.43) | MAPTNLRP3 | |
| SCHEMBL27074754 | 0.69 | NLRP3 (0.36) | NLRP3 | |
| SCHEMBL4219463 | 0.69 | NR3C1 (0.54) | NR3C1 | |
| SCHEMBL28742526 | 0.69 | ATM (0.39) | SCN9ACASRPPARACNR1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119095828-A | Indazole compound, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-12-06 | — | — | CN | disclosed |
| WO-2023186058-A1 | INDAZOLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2023-10-05 | — | — | WO | disclosed |