Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP9 | P55211 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13719503 | 0.76 | DYRK2 (0.61) | MAPTSMN1; SMN2ALDH1A1MITFLMNA | |
| SCHEMBL19348947 | 0.76 | DYRK2 (0.61) | MAPTSMN1; SMN2ALDH1A1MITFLMNA | |
| SCHEMBL13719504 | 0.76 | DYRK2 (0.61) | MAPTSMN1; SMN2ALDH1A1MITFLMNA | |
| SCHEMBL30955850 | 0.75 | MAPT (0.35) | MAPTALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL16426792 | 0.74 | IKBKB (0.54) | MAPTALDH1A1LMNAHTTNPC1 | |
| SCHEMBL16426791 | 0.74 | IKBKB (0.54) | MAPTALDH1A1LMNAHTTNPC1 | |
| SCHEMBL28129799 | 0.73 | MAOB (0.43) | MAPTSMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL9484204 | 0.72 | MAPT (0.33) | MAPTCA12 | |
| SCHEMBL28628275 | 0.72 | MAPT (0.33) | MAPTCA12 | |
| SCHEMBL27515150 | 0.72 | SOS1 (0.68) | MAPTSMN1; SMN2ALDH1A1MITFLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836164-A | 2-indoline imine spiro-pyrrolidone compound and crystal form, preparation method and application thereof | 成都大学 | 2023-10-03 | — | — | CN | claimed |
| CN-116836164-A | 2-indoline imine spiro-pyrrolidone compound and crystal form, preparation method and application thereof | 成都大学 | 2023-10-03 | — | — | CN | disclosed |