Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 4/20 | 0.33 |
| ▸ | SNCA | P37840 | 4/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28628275 | 0.79 | MAPT (0.33) | MAPTMEN1KMT2AJAK2APP | |
| SCHEMBL9484204 | 0.79 | MAPT (0.33) | MAPTMEN1KMT2AJAK2APP | |
| SCHEMBL30603084 | 0.75 | MAPT (0.53) | MAPTALDH1A1CA12CYP1A2CYP2D6 | |
| SCHEMBL3692772 | 0.72 | NOS2 (0.41) | JAK2NOS2ALDH1A1GAACA12 | |
| SCHEMBL15291319 | 0.72 | JAK2 (0.39) | MEN1KMT2AJAK2NOS2ALDH1A1 | |
| SCHEMBL30785015 | 0.72 | NOS2 (0.41) | JAK2NOS2ALDH1A1GAACA12 | |
| SCHEMBL3692774 | 0.72 | NOS2 (0.41) | JAK2NOS2ALDH1A1GAACA12 | |
| SCHEMBL28129799 | 0.69 | MAOB (0.43) | MAPTMEN1KMT2AJAK2ALDH1A1 | |
| SCHEMBL31372632 | 0.69 | — | — | |
| SCHEMBL29556997 | 0.68 | JAK2 (0.36) | MAPTJAK2NOS2GAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184701-A | Phosphono-substituted 3-methyleneoxindole compound and preparation and application thereof | 浙江工业大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-118184568-A | Sulfonyl compound containing oxindole skeleton and preparation and application thereof | 浙江工业大学 | 2024-06-14 | — | — | CN | disclosed |