Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 4/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30604339 | 0.81 | KCNN4 (0.46) | KCNN4HTR7CTSSCTSKCTSL | |
| SCHEMBL12772066 | 0.79 | TDP1 (0.36) | KCNN4HTR7ALDH1A1MAPTEGFR | |
| SCHEMBL30604347 | 0.79 | KCNN4 (0.44) | KCNN4HTR7CTSSCTSKCTSL | |
| SCHEMBL6048623 | 0.79 | KCNN4 (0.49) | KCNN4HTR7ALDH1A1LMNAMAPT | |
| SCHEMBL30604355 | 0.75 | AR (0.43) | KCNN4CTSSCTSKCTSLALDH1A1 | |
| SCHEMBL31166945 | 0.73 | PTPN1 (0.42) | KCNN4ALDH1A1MAPTEGFRTDP1 | |
| SCHEMBL12773931 | 0.70 | PTPN1 (0.31) | HTR7MAPTEGFRKDM4EPTPN1 | |
| SCHEMBL23092046 | 0.69 | KCNN4 (0.43) | KCNN4HTR7ALDH1A1MAPTEGFR | |
| SCHEMBL16056052 | 0.69 | FGFR1 (0.42) | KCNN4ALDH1A1LMNAMAPTEGFR | |
| SCHEMBL30741239 | 0.69 | CA12 (0.48) | KCNN4ALDH1A1LMNAMAPTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981251-B | Dibenzofuran derivative cathepsin K inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-11-21 | — | — | CN | disclosed |