Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16055919 | 0.85 | PTPN1 (0.37) | KCNN4HTR7RAB9ALMNASMN1; SMN2 | |
| SCHEMBL23092046 | 0.85 | KCNN4 (0.43) | KCNN4HTR7RAB9ASMN1; SMN2ADRB2 | |
| SCHEMBL30604339 | 0.84 | KCNN4 (0.46) | KCNN4CTSSCTSKCTSLHTR7 | |
| SCHEMBL6048623 | 0.81 | KCNN4 (0.49) | KCNN4HTR7RAB9ALMNAADRB2 | |
| SCHEMBL30604342 | 0.79 | KCNN4 (0.43) | KCNN4CTSSCTSKCTSLHTR7 | |
| SCHEMBL30604355 | 0.78 | AR (0.43) | KCNN4CTSSCTSKCTSLRAB9A | |
| SCHEMBL29572501 | 0.77 | HTR7 (0.53) | HTR7RAB9ALMNASMN1; SMN2NPC1 | |
| SCHEMBL755670 | 0.77 | HTR7 (0.53) | HTR7RAB9ALMNASMN1; SMN2NPC1 | |
| SCHEMBL31166945 | 0.75 | PTPN1 (0.42) | KCNN4SMN1; SMN2PTPN1MAOB | |
| SCHEMBL19770514 | 0.75 | TOP1 (0.44) | HTR7LMNAHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981251-B | Dibenzofuran derivative cathepsin K inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-11-21 | — | — | CN | disclosed |