Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30604339 | 0.80 | KCNN4 (0.46) | KCNN4ALDH1A1CTSLCTSSCTSK | |
| SCHEMBL29530857 | 0.80 | GAA (0.51) | ALDH1A1POLBGAAHPGDTSHR | |
| SCHEMBL18587828 | 0.80 | GAA (0.51) | ALDH1A1POLBGAAHPGDTSHR | |
| SCHEMBL30604347 | 0.78 | KCNN4 (0.44) | KCNN4CTSLCTSSCTSKNPC1 | |
| SCHEMBL6048623 | 0.78 | KCNN4 (0.49) | KCNN4ALDH1A1HPGDRAB9A | |
| SCHEMBL11937448 | 0.77 | AR (0.40) | ARKCNN4ALDH1A1HPGDTSHR | |
| SCHEMBL30604342 | 0.75 | KCNN4 (0.43) | KCNN4ALDH1A1GAACTSLCTSS | |
| SCHEMBL21736886 | 0.75 | SSTR4 (0.41) | ALDH1A1POLBGAAHPGDTSHR | |
| SCHEMBL12284280 | 0.74 | AR (0.50) | ARALDH1A1POLBGAAHPGD | |
| SCHEMBL28299496 | 0.74 | AR (0.47) | ARKCNN4ALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981251-B | Dibenzofuran derivative cathepsin K inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-11-21 | — | — | CN | disclosed |