Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30604347 | 0.84 | KCNN4 (0.44) | KCNN4HTR7CTSLCTSSCTSK | |
| SCHEMBL6048623 | 0.84 | KCNN4 (0.49) | KCNN4HTR7CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL30604342 | 0.81 | KCNN4 (0.43) | KCNN4HTR7CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30604355 | 0.80 | AR (0.43) | KCNN4ALDH1A1TSHRCTSLCTSS | |
| SCHEMBL31166945 | 0.78 | PTPN1 (0.42) | KCNN4ALDH1A1TDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL16056052 | 0.77 | FGFR1 (0.42) | KCNN4ALDH1A1LMNAERN1KDM4E | |
| SCHEMBL31360728 | 0.76 | CA1 (0.62) | CYP1A2ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL2101135 | 0.76 | CA1 (0.62) | CYP1A2ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL10227173 | 0.74 | ALDH1A1 (0.53) | HTR7CYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL23092046 | 0.74 | KCNN4 (0.43) | KCNN4HTR7CYP1A2ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981251-B | Dibenzofuran derivative cathepsin K inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-11-21 | — | — | CN | disclosed |