Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | DHPS | P49366 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28638924 | 1.00 | GRM5 (0.52) | GRM5LMNAHTTTSHRSMN1; SMN2 | |
| SCHEMBL30604579 | 0.89 | GRM5 (0.58) | GRM5LMNASMN1; SMN2L3MBTL1NCOA3 | |
| SCHEMBL28641201 | 0.89 | GRM5 (0.58) | GRM5LMNASMN1; SMN2L3MBTL1NCOA3 | |
| SCHEMBL28633468 | 0.88 | KMT2A (0.46) | LMNAHTTTSHRKMT2AMEN1 | |
| SCHEMBL30604607 | 0.88 | KMT2A (0.51) | GRM5LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL28636452 | 0.88 | KMT2A (0.51) | GRM5LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL30604585 | 0.83 | MEN1 (0.47) | GRM5LMNAHTTTSHRSMN1; SMN2 | |
| SCHEMBL28633459 | 0.83 | MEN1 (0.47) | GRM5LMNAHTTTSHRSMN1; SMN2 | |
| SCHEMBL31134765 | 0.82 | GRM5 (0.60) | GRM5KMT2AMEN1DRD4 | |
| SCHEMBL30604561 | 0.79 | GRM5 (0.57) | GRM5LMNASMN1; SMN2L3MBTL1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493438-B | Tetrahydroisoquinoline compounds | 南京再明医药有限公司 | 2023-10-20 | — | — | CN | disclosed |