Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | DHPS | P49366 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28636452 | 1.00 | KMT2A (0.51) | KMT2AGRM5SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL28633459 | 0.91 | MEN1 (0.47) | KMT2AGRM5SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL30604585 | 0.91 | MEN1 (0.47) | KMT2AGRM5SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL28633462 | 0.89 | KMT2A (0.53) | KMT2AMEN1MAPTDHPS | |
| SCHEMBL30604584 | 0.88 | GRM5 (0.52) | KMT2AGRM5SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL28638924 | 0.88 | GRM5 (0.52) | KMT2AGRM5SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL28652352 | 0.80 | KMT2A (0.48) | KMT2AALDH1A1HTT | |
| SCHEMBL30604612 | 0.80 | KMT2A (0.47) | KMT2ASMN1; SMN2MEN1ALDH1A1LMNA | |
| SCHEMBL28641201 | 0.79 | GRM5 (0.58) | KMT2AGRM5SMN1; SMN2MEN1LMNA | |
| SCHEMBL30604579 | 0.79 | GRM5 (0.58) | KMT2AGRM5SMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493438-B | Tetrahydroisoquinoline compounds | 南京再明医药有限公司 | 2023-10-20 | — | — | CN | disclosed |