Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1136684 | 0.88 | EPHX2 (0.45) | MEN1KMT2ALMNATHRBBLM | |
| SCHEMBL16495208 | 0.86 | LMNA (0.48) | MEN1KMT2ALMNATHRBBLM | |
| SCHEMBL8972675 | 0.81 | LMNA (0.43) | MEN1KMT2ALMNATHRBBLM | |
| SCHEMBL8972623 | 0.81 | MEN1 (0.43) | MEN1KMT2ALMNATHRBBLM | |
| SCHEMBL7388305 | 0.77 | LMNA (0.39) | MEN1KMT2ALMNATHRBBLM | |
| SCHEMBL7542257 | 0.77 | LMNA (0.46) | MEN1KMT2ALMNATHRBBLM | |
| SCHEMBL9712135 | 0.77 | LMNA (0.46) | MEN1KMT2ALMNATHRBBLM | |
| SCHEMBL9711980 | 0.77 | LMNA (0.46) | MEN1KMT2ALMNATHRBBLM | |
| SCHEMBL6097634 | 0.75 | KEAP1 (0.53) | MEN1KMT2ALMNATDP1ALDH1A1 | |
| Alcohol SCHEMBL9499504 | 0.74 | LMNA (0.43) | MEN1KMT2ALMNATHRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476616-B | Piperazinyl methanone NAAA inhibitors | 加利福尼亚大学董事会 | 2023-10-13 | — | — | CN | disclosed |