Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30607573 | 0.87 | KDM4E (0.61) | KDM4ERECQLALDH1A1MAPTHSD11B1 | |
| SCHEMBL30607636 | 0.82 | ALDH1A1 (0.54) | KDM4ERECQLALDH1A1MAPTKCNJ1 | |
| SCHEMBL30607671 | 0.80 | KDM4E (0.55) | KDM4ERECQLALDH1A1MAPTHSD11B1 | |
| SCHEMBL26111523 | 0.80 | KDM4E (0.55) | KDM4ERECQLALDH1A1MAPTHSD11B1 | |
| SCHEMBL30607634 | 0.79 | KIF18A (0.38) | ALDH1A1 | |
| SCHEMBL3291338 | 0.75 | KDM4E (0.54) | KDM4ERECQLALDH1A1MAPTHSD11B1 | |
| SCHEMBL29609043 | 0.75 | KDM4E (0.54) | KDM4ERECQLALDH1A1MAPTHSD11B1 | |
| SCHEMBL3291180 | 0.74 | KDM4E (0.67) | KDM4ERECQLALDH1A1MAPTHSD11B1 | |
| SCHEMBL2750963 | 0.73 | KDM4E (0.58) | KDM4ERECQLALDH1A1MAPTHSD11B1 | |
| SCHEMBL565864 | 0.73 | KDM4E (0.61) | KDM4ERECQLALDH1A1MAPTHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186065-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-10-05 | — | — | WO | disclosed |