Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | JAK2 | O60674 | 2/20 | 0.53 |
| ▸ | JAK3 | P52333 | 2/20 | 0.53 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26111523 | 1.00 | KDM4E (0.55) | KDM4ERECQLJAK2JAK3ACKR3 | |
| SCHEMBL30607573 | 0.92 | KDM4E (0.61) | KDM4ERECQLJAK2JAK3ACKR3 | |
| SCHEMBL1514427 | 0.81 | KDM4E (0.64) | KDM4ERECQLJAK2JAK3ACKR3 | |
| SCHEMBL5615322 | 0.81 | KDM4E (0.64) | KDM4ERECQLJAK2JAK3ACKR3 | |
| SCHEMBL30607643 | 0.80 | KDM4E (0.51) | KDM4ERECQLALDH1A1MAPTGRM1 | |
| Hydrochloric Acid SCHEMBL1514615 | 0.80 | KDM4E (0.62) | KDM4ERECQLJAK2JAK3ACKR3 | |
| SCHEMBL3288371 | 0.80 | KDM4E (0.62) | KDM4ERECQLACKR3ALDH1A1MAPT | |
| SCHEMBL29907658 | 0.79 | CYP2D6 (0.47) | JAK2JAK3GRM1PDE10AELANE | |
| SCHEMBL3291180 | 0.77 | KDM4E (0.67) | KDM4ERECQLALDH1A1MAPTHSD11B1 | |
| SCHEMBL3290456 | 0.77 | KDM4E (0.58) | KDM4ERECQLALDH1A1MAPTGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186065-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-10-05 | — | — | WO | disclosed |