Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.33 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20738212 | 0.80 | KDM4E (0.46) | CREBBPKDM4EBRD4KMT2AERCC5 | |
| SCHEMBL21877551 | 0.76 | BRD4 (0.42) | CREBBPKDM4EBRD4ERCC5FEN1 | |
| SCHEMBL21484069 | 0.76 | CREBBP (0.41) | CREBBPKDM4EBRD4ERCC5FEN1 | |
| SCHEMBL23381882 | 0.76 | CREBBP (0.41) | CREBBPKDM4EBRD4ERCC5FEN1 | |
| SCHEMBL27748840 | 0.76 | TDO2 (0.41) | CREBBPKDM4EBRD4KMT2AERCC5 | |
| SCHEMBL21706148 | 0.76 | CREBBP (0.41) | CREBBPKDM4EBRD4ERCC5FEN1 | |
| SCHEMBL24352877 | 0.74 | CYP3A4 (0.43) | CREBBPKDM4EBRD4ERCC5FEN1 | |
| SCHEMBL30332120 | 0.74 | CREBBP (0.40) | CREBBPKDM4EBRD4KMT2AERCC5 | |
| SCHEMBL31055053 | 0.73 | CREBBP (0.41) | CREBBPKDM4EBRD4ERCC5FEN1 | |
| SCHEMBL31055062 | 0.73 | ERCC5 (0.45) | CREBBPKDM4EBRD4KMT2AERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186065-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-10-05 | — | — | WO | disclosed |