SCHEMBL31055053

SCHEMBL31055053

N#Cc1ccccc1-n1cc(C=O)cn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CREBBP Q92793 2/20 0.41
BRD4 O60885 1/20 0.40
ERCC5 P28715 1/20 0.39
FEN1 P39748 1/20 0.39
KDM4E B2RXH2 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
MAPT P10636 1/20 0.35
MTOR P42345 3/20 0.35
HSP90AA1 P07900 1/20 0.35
HTR1A P08908 1/20 0.34
ADRA1D P25100 1/20 0.34
ADRA1A P35348 1/20 0.34
ADRA1B P35368 1/20 0.34
ALKBH1 Q13686 1/20 0.34
AXL P30530 1/20 0.34
GRM5 P41594 1/20 0.33
SLC2A1 P11166 1/20 0.33
SLC2A2 P11168 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27748840 0.80 TDO2 (0.41) CREBBPBRD4ERCC5FEN1KDM4E
SCHEMBL11972538 0.77 MTOR (0.33) KDM4ESMN1; SMN2NPC1RAB9AMTOR
SCHEMBL15181538 0.76 MTOR (0.54) SMN1; SMN2NPC1RAB9AMTOR
SCHEMBL30037462 0.76 MTOR (0.54) SMN1; SMN2NPC1RAB9AMTOR
SCHEMBL5661512 0.76 ALDH1A1 (0.46) KDM4ESMN1; SMN2NPC1RAB9AMTOR
SCHEMBL23036928 0.76 MTOR (0.54) KDM4ESMN1; SMN2NPC1RAB9AMTOR
SCHEMBL21484069 0.76 CREBBP (0.41) CREBBPBRD4ERCC5FEN1KDM4E
SCHEMBL21877551 0.76 BRD4 (0.42) CREBBPBRD4ERCC5FEN1KDM4E
SCHEMBL20738212 0.76 KDM4E (0.46) CREBBPBRD4ERCC5FEN1KDM4E
SCHEMBL23381882 0.76 CREBBP (0.41) CREBBPBRD4ERCC5FEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114341131-B Novel oxadiazole compounds comprising 5-membered heteroaromatic rings for controlling or preventing phytopathogenic fungi PI工业有限公司 2024-09-03 CN disclosed