Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 3/20 | 0.42 |
| ▸ | JAK3 | P52333 | 3/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26115105 | 1.00 | PDE10A (0.46) | PDE10AELANEHRH4HRH3JAK2 | |
| SCHEMBL30607703 | 0.92 | KMT2A (0.40) | PDE10AELANEHRH4HRH3JAK2 | |
| SCHEMBL30607634 | 0.80 | KIF18A (0.38) | JAK2JAK3CYP2D6 | |
| SCHEMBL3287139 | 0.80 | CNR2 (0.44) | PDE10A | |
| SCHEMBL3289773 | 0.77 | KMT2A (0.40) | PDE10AELANE | |
| SCHEMBL3291160 | 0.77 | KCNMA1 (0.39) | PDE10AJAK2JAK3 | |
| SCHEMBL3296150 | 0.76 | MAP4K4 (0.41) | PDE10AJAK2JAK3MAP4K4 | |
| SCHEMBL30607671 | 0.76 | KDM4E (0.55) | PDE10AELANEJAK2JAK3DRD2 | |
| SCHEMBL26111523 | 0.76 | KDM4E (0.55) | PDE10AELANEJAK2JAK3DRD2 | |
| SCHEMBL16814991 | 0.76 | KMT2A (0.43) | PDE10AELANEJAK2JAK3DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186065-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-10-05 | — | — | WO | disclosed |