Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 8/20 | 0.37 |
| ▸ | CCR2 | P41597 | 4/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30608962 | 0.89 | ESR1 (0.38) | HRH1HRH2ESR1KCNH2CYP2D6 | |
| SCHEMBL30608923 | 0.84 | ROCK2 (0.46) | HRH1HRH2ROCK2CCR2ROCK1 | |
| SCHEMBL30608972 | 0.82 | NOS2 (0.47) | HRH1HRH2DRD2DRD3 | |
| SCHEMBL25851871 | 0.81 | ESR1 (0.36) | HRH1HRH2AXLFLT3TYRO3 | |
| SCHEMBL25851884 | 0.81 | ESR1 (0.36) | HRH1HRH2AXLFLT3TYRO3 | |
| SCHEMBL25494073 | 0.79 | HRH2 (0.42) | HRH1HRH2ROCK2CCR2ROCK1 | |
| SCHEMBL30346597 | 0.79 | HRH2 (0.42) | HRH1HRH2ROCK2CCR2ROCK1 | |
| SCHEMBL23098104 | 0.78 | HRH4 (0.47) | AXLCHEK1CHEK2 | |
| SCHEMBL30422610 | 0.72 | ROCK2 (0.43) | ROCK2CCR2ROCK1 | |
| SCHEMBL30346693 | 0.70 | KDM4E (0.44) | ESR1KCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116964049-A | Estrogen receptor modulators | 里科瑞尔姆IP控股有限责任公司 | 2023-10-27 | — | — | CN | disclosed |