Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 10/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30608922 | 0.84 | HRH1 (0.41) | ROCK2ROCK1HRH2HRH1CCR2 | |
| SCHEMBL23098104 | 0.83 | HRH4 (0.47) | HRH4 | |
| SCHEMBL30608962 | 0.72 | ESR1 (0.38) | HRH2HRH1 | |
| SCHEMBL2369918 | 0.72 | HCAR3 (0.42) | ROCK2ROCK1 | |
| SCHEMBL13633528 | 0.72 | ROCK2 (0.87) | ROCK2ROCK1CCR2 | |
| SCHEMBL22877113 | 0.69 | KDM4E (0.50) | HRH4 | |
| SCHEMBL5847287 | 0.69 | KDM4E (0.46) | HRH4 | |
| SCHEMBL30608947 | 0.69 | NOS2 (0.50) | NOS2 | |
| SCHEMBL30183229 | 0.68 | KDM4E (0.53) | HRH4 | |
| SCHEMBL9901706 | 0.68 | KDM4E (0.53) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116964049-A | Estrogen receptor modulators | 里科瑞尔姆IP控股有限责任公司 | 2023-10-27 | — | — | CN | disclosed |