SCHEMBL30608947

SCHEMBL30608947

CCCN1CC(Nc2ccccn2)C1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 1/20 0.50
CCNA2 P20248 1/20 0.41
CDK2 P24941 1/20 0.41
HTT P42858 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
GAA P10253 1/20 0.39
DRD2 P14416 1/20 0.39
DRD4 P21917 1/20 0.39
DRD3 P35462 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
KDM5A P29375 1/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
ALOX12 P18054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30608951 0.82 NOS2 (0.42) NOS2CCNA2CDK2HTTGAA
SCHEMBL30413253 0.77 NOS2 (0.52) NOS2HTTSMN1; SMN2DRD2DRD4
SCHEMBL5315582 0.76 NOS2 (0.64) NOS2CCNA2CDK2HTTDRD2
SCHEMBL13118510 0.75 NOS2 (0.56) NOS2CCNA2CDK2DRD2DRD4
SCHEMBL12440506 0.74 NOS2 (0.62) NOS2CCNA2CDK2DRD2DRD4
Hydrochloric Acid SCHEMBL27710837 0.73 NOS2 (0.60) NOS2CCNA2CDK2DRD2DRD4
SCHEMBL526424 0.73 NOS2 (0.55) NOS2SMN1; SMN2GAAMEN1KMT2A
SCHEMBL30608972 0.72 NOS2 (0.47) NOS2CCNA2CDK2HTTDRD2
SCHEMBL11777245 0.71 SIGMAR1 (0.56) NOS2GAADRD2DRD4DRD3
SCHEMBL13326542 0.71 DRD2 (0.65) DRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116964049-A Estrogen receptor modulators 里科瑞尔姆IP控股有限责任公司 2023-10-27 CN disclosed