⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10515993 | 0.84 | — | — | |
| SCHEMBL6489205 | 0.69 | — | — | |
| SCHEMBL6216657 | 0.69 | — | — | |
| SCHEMBL16529635 | 0.69 | — | — | |
| SCHEMBL1000577 | 0.69 | — | — | |
| SCHEMBL297937 | 0.62 | ABCB1 (0.31) | — | |
| SCHEMBL9146098 | 0.62 | — | — | |
| SCHEMBL3435214 | 0.62 | — | — | |
| SCHEMBL2148228 | 0.60 | FABP4 (0.31) | — | |
| SCHEMBL1091821 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060416-B1 | NEW BETA-LACTAM ACETIC ACID DERIVATIVES, THE PROCESS FOR PREPARING THEM, AND THEIR USE AS INTERMEDIATES FOR 1-AZABICYCLO(3.2.0.)HEPT-2-ENE ANTIBIOTICS | GRUPPO LEPETIT S.P.A. (IT) | 1986-08-20 | — | — | EP | claimed |
| EP-0060416-A1 | New beta-lactam acetic acid derivatives, the process for preparing them, and their use as intermediates for 1-azabicyclo(3.2.0.)hept-2-ene antibiotics | GRUPPO LEPETIT S.P.A. (IT) | 1982-09-22 | — | — | EP | claimed |
| EP-0008514-B1 | BETA-LACTAM ANTI-BACTERIALS, COMPOSITIONS CONTAINING THEM AND A PROCESS FOR THEIR PREPARATION | BEECHAM GROUP PLC (GB) | 1982-01-20 | — | — | EP | claimed |
| US-12624382-B2 | Beta-lactam compounds and methods of use thereof | THE UNIVERSITY OF HONG KONG (HK) | 2026-05-12 | — | — | US | disclosed |
| EP-3430013-A1 | CARBAPENEM COMPOUNDS | Orchid Pharma Limited (IN) | 2019-01-23 | — | — | EP | disclosed |
| WO-2017158616-A1 | CARBAPENEM COMPOUNDS | ORCHID PHARMA LTD. (IN) | 2017-09-21 | — | — | WO | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |
| EP-0090366-B1 | 1-AZABICYCLO(3.2.0)HEPT-2-ENE-2-CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-11-25 | — | — | EP | disclosed |
| US-4640915-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-02-03 | — | — | US | disclosed |
| EP-0060416-B1 | NEW BETA-LACTAM ACETIC ACID DERIVATIVES, THE PROCESS FOR PREPARING THEM, AND THEIR USE AS INTERMEDIATES FOR 1-AZABICYCLO(3.2.0.)HEPT-2-ENE ANTIBIOTICS | GRUPPO LEPETIT S.P.A. (IT) | 1986-08-20 | — | — | EP | disclosed |
| US-4576746-A | Novel β-lactam acetic acid derivatives | GRUPPO LEPETIT, S.P.A. (IT) | 1986-03-18 | — | — | US | disclosed |
| EP-0090366-A1 | 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-10-05 | — | — | EP | disclosed |
| EP-0008888-B1 | BETA-LACTAM ANTIBACTERIAL COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1983-09-21 | — | — | EP | disclosed |
| US-4377591-A | CARBAPENICILLIN ANTIBIOTICS | SANKYO COMPANY, LIMITED (JP) | 1983-03-22 | — | — | US | disclosed |
| EP-0061231-A1 | Process for the preparation of azabicyclo(3.2.0)-hept-2-ene derivatives | BEECHAM GROUP PLC (GB) | 1982-09-29 | — | — | EP | disclosed |
| EP-0060612-A1 | Process for the preparation of azabicyclo(3.2.0)-hept-2-ene derivatives | BEECHAM GROUP PLC (GB) | 1982-09-22 | — | — | EP | disclosed |
| EP-0060416-A1 | New beta-lactam acetic acid derivatives, the process for preparing them, and their use as intermediates for 1-azabicyclo(3.2.0.)hept-2-ene antibiotics | GRUPPO LEPETIT S.P.A. (IT) | 1982-09-22 | — | — | EP | disclosed |
| EP-0060416-A1 | New beta-lactam acetic acid derivatives, the process for preparing them, and their use as intermediates for 1-azabicyclo(3.2.0.)hept-2-ene antibiotics | GRUPPO LEPETIT S.P.A. (IT) | 1982-09-22 | — | — | EP | disclosed |
| EP-0005348-B1 | CARBAPENEM DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1982-09-22 | — | — | EP | disclosed |
| EP-0008888-A1 | Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1980-03-19 | — | — | EP | disclosed |