Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.82 |
| ▸ | IGF1R | P08069 | 3/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | YWHAG | P61981 | 1/20 | 0.54 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.52 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.49 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20604743 | 1.00 | APP (0.82) | APPIGF1RALOX15TDP1TRPV1 | |
| SCHEMBL20604780 | 0.99 | APP (0.80) | APPIGF1RALOX15TDP1TRPV1 | |
| SCHEMBL20604772 | 0.99 | APP (0.80) | APPIGF1RALOX15TDP1TRPV1 | |
| SCHEMBL30610035 | 0.99 | APP (0.80) | APPIGF1RALOX15TDP1TRPV1 | |
| SCHEMBL30610044 | 0.99 | APP (0.80) | APPIGF1RALOX15TDP1TRPV1 | |
| SCHEMBL20914966 | 0.96 | APP (0.84) | APPIGF1RALOX15TDP1TRPV1 | |
| SCHEMBL490480 | 0.90 | APP (1.00) | APPIGF1RALOX15TDP1TRPV1 | |
| SCHEMBL22353624 | 0.90 | APP (0.84) | APPIGF1RALOX15TDP1YWHAG | |
| SCHEMBL9491435 | 0.85 | TDP1 (0.79) | APPTDP1FFAR1ALOX5 | |
| SCHEMBL20914999 | 0.83 | YWHAG (0.68) | APPIGF1RALOX15TDP1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240425441-A9 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | ICOSA PHARMA INC. (CA) | 2024-12-26 | — | — | US | claimed |
| US-20230391711-A1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-12-07 | — | — | US | claimed |
| US-20240425441-A9 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | ICOSA PHARMA INC. (CA) | 2024-12-26 | — | — | US | disclosed |
| US-20230391711-A1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-12-07 | — | — | US | disclosed |
| US-11760715-B2 | Modulators of lipoxygenase and cyclooxygenase enzyme activity | UNIVERSITÉ DE MONCTON (CA) | 2023-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240425441-A9 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | ALOX12, ALOX15B, ALOX5 | APP 3143/4885IGF1R 3825/4885ALOX15 4/4885 |
| US-11760715-B2 | Modulators of lipoxygenase and cyclooxygenase enzyme activity | ALOX12, ALOX15B, ALOX5 | APP 3143/4885IGF1R 3825/4885ALOX15 4/4885 |
| US-20230391711-A1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | ALOX12, ALOX15B, ALOX5 | APP 3143/4885IGF1R 3825/4885ALOX15 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.