Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK1 | P06870 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 7/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30612338 | 0.90 | KLK1 (0.48) | KLK1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL29264850 | 0.88 | KDM4E (0.52) | KLK1PLA2G2APLA2G1BMAPK8NOTUM | |
| SCHEMBL30612324 | 0.87 | NOTUM (0.45) | NOTUMPTGDR2TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL30612320 | 0.87 | KMT2A (0.52) | NOTUMTSHRMAPK1KMT2AMAPT | |
| SCHEMBL29264884 | 0.82 | MAPK8 (0.50) | KLK1PLA2G2APLA2G1BMAPK8NOTUM | |
| SCHEMBL30612318 | 0.80 | GRIA2 (0.48) | NOTUMPTGDR2TSHRKMT2AMAPT | |
| SCHEMBL29264863 | 0.79 | SLC6A4 (0.45) | KLK1MAPK8KMT2AMAPT | |
| SCHEMBL29264847 | 0.78 | KDM4E (0.50) | MAPK8NOTUMTSHRKMT2AMAPT | |
| SCHEMBL29264882 | 0.78 | KDM4E (0.47) | PLA2G2AMAPK8NOTUMTSHRKMT2A | |
| SCHEMBL29264859 | 0.77 | NOTUM (0.58) | NOTUMTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854631-B | 4-Aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-116854631-A | 4-aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2023-10-10 | — | — | CN | disclosed |