Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29264884 | 0.92 | MAPK8 (0.50) | KDM4EMAPK8PLA2G2AKMT2ASMN1; SMN2 | |
| SCHEMBL29264882 | 0.89 | KDM4E (0.47) | KDM4EMAPK8PLA2G2AKMT2ASMN1; SMN2 | |
| SCHEMBL30612331 | 0.88 | KLK1 (0.48) | MAPK8PLA2G2AKMT2ASMN1; SMN2PLA2G1B | |
| SCHEMBL29264863 | 0.88 | SLC6A4 (0.45) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29264847 | 0.88 | KDM4E (0.50) | KDM4EMAPK8KMT2ASMN1; SMN2TSHR | |
| SCHEMBL29264871 | 0.87 | NPSR1 (0.47) | KDM4EMAPK8PLA2G2AKMT2ASMN1; SMN2 | |
| SCHEMBL29264853 | 0.86 | KDM4E (0.47) | KDM4EMAPK8KMT2ASMN1; SMN2TSHR | |
| SCHEMBL29264868 | 0.83 | MAPK8 (0.50) | KDM4EMAPK8KMT2ASMN1; SMN2TSHR | |
| SCHEMBL29264864 | 0.81 | NPSR1 (0.47) | KDM4EMAPK8PLA2G2AKMT2ASMN1; SMN2 | |
| SCHEMBL29264859 | 0.78 | NOTUM (0.58) | KDM4ESMN1; SMN2TSHRNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854631-B | 4-Aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-116854631-A | 4-aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2023-10-10 | — | — | CN | disclosed |