SCHEMBL30612367

SCHEMBL30612367

NCCCC[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 7/20 0.62
OPRD1 P41143 4/20 0.54
OPRK1 P41145 1/20 0.49
ERAP2 Q6P179 1/20 0.48
LNPEP Q9UIQ6 1/20 0.48
NTSR2 O95665 2/20 0.48
NTSR1 P30989 2/20 0.48
F2 P00734 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31114326 0.94 OPRM1 (0.57) OPRM1OPRD1OPRK1ERAP2LNPEP
SCHEMBL31114531 0.93 OPRM1 (0.62) OPRM1OPRD1NTSR2NTSR1
SCHEMBL31519062 0.92 OPRM1 (0.64) OPRM1OPRD1NTSR2NTSR1F2
SCHEMBL31114393 0.91 OPRM1 (0.62) OPRM1OPRD1NTSR2NTSR1F2
SCHEMBL30839278 0.89 OPRM1 (0.57) OPRM1OPRD1OPRK1NTSR2NTSR1
SCHEMBL31114331 0.89 OPRM1 (0.62) OPRM1OPRD1NTSR2NTSR1
SCHEMBL31114433 0.89 OPRM1 (0.65) OPRM1OPRD1NTSR2NTSR1
SCHEMBL31114345 0.89 OPRM1 (0.58) OPRM1OPRD1NTSR2NTSR1F2
SCHEMBL31114060 0.88 OPRM1 (0.61) OPRM1OPRD1NTSR2NTSR1F2
SCHEMBL31114372 0.88 OPRM1 (0.59) OPRM1OPRD1NTSR2NTSR1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218016-A1 PEPTIDES AND THEIR USE IN THE TREATMENT OF INFLAMMATION Enlitisa (Shanghai) Pharmaceutical Co., Ltd. (CN) 2024-07-04 US disclosed
US-20230331792-A1 NEW MULTI-FUNCTIONAL OLIGOPEPTIDES Enlitisa (Shanghai) Pharmaceutical Co., Ltd. (CN) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331792-A1 NEW MULTI-FUNCTIONAL OLIGOPEPTIDES VIP, MLX, IAPP OPRM1 416/4885OPRD1 389/4885OPRK1 721/4885
US-20240218016-A1 PEPTIDES AND THEIR USE IN THE TREATMENT OF INFLAMMATION VIP, ARGLU1, NGLY1 OPRM1 722/4885OPRD1 829/4885OPRK1 841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.