Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 11/20 | 0.35 |
| ▸ | TDO2 | P48775 | 16/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4429292 | 0.74 | CDC25A (0.50) | — | |
| SCHEMBL11885001 | 0.70 | IDO1 (0.46) | IDO1TDO2 | |
| SCHEMBL16836473 | 0.64 | IDO1 (0.54) | IDO1TDO2 | |
| SCHEMBL29796610 | 0.64 | IDO1 (0.54) | IDO1TDO2 | |
| SCHEMBL6588265 | 0.64 | PARP1 (0.46) | — | |
| SCHEMBL8887886 | 0.64 | KDM4E (0.45) | — | |
| SCHEMBL12205521 | 0.64 | MAOA (0.67) | — | |
| SCHEMBL19309592 | 0.63 | IDO1 (0.33) | IDO1TDO2 | |
| SCHEMBL21315928 | 0.63 | TDO2 (0.35) | IDO1TDO2 | |
| SCHEMBL19937653 | 0.63 | TDO2 (0.38) | IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295179-A1 | EIF4A-INHIBITING COMPOUNDS AND METHODS RELATED THERETO | EFFECTOR THERAPEUTICS, INC. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295179-A1 | EIF4A-INHIBITING COMPOUNDS AND METHODS RELATED THERETO | EIF4A1, EIF4A2, EIF4A3 | IDO1 4359/4885TDO2 3237/4885F7 2667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.