⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30558522 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL6363468 | 0.98 | RAB9A (0.55) | — | |
| SCHEMBL318096 | 0.84 | KCNH2 (0.57) | — | |
| SCHEMBL229747 | 0.82 | RAB9A (0.59) | — | |
| SCHEMBL18913402 | 0.81 | RAB9A (0.53) | — | |
| SCHEMBL19151683 | 0.81 | RAB9A (0.53) | — | |
| Isophthalic Acid SCHEMBL27663245 | 0.80 | GRM5 (0.54) | — | |
| Dimethylamine SCHEMBL21836445 | 0.78 | CCR1 (0.60) | — | |
| SCHEMBL19915750 | 0.78 | — | — | |
| SCHEMBL2007460 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100424082-C | 4- (piperidinyl-pyrrolidinyl-alkyl-ureido) -quinolines as urotensin II receptor antagonists | ACTELION PHARMACEUTICALS LTD (CH) | 2008-10-08 | — | — | CN | claimed |
| CN-1617869-A | 4-(piperidyl- and pyrrolidyl-alkyl-ureido) -quinolines as urotensin ii receptor antagonists | ACTELION PHARMACEUTICALS LTD (CH) | 2005-05-18 | — | — | CN | claimed |
| JP-60067463-A | — | — | None | — | — | JP | disclosed |
| CN-114072393-B | 3-Amino-4H-benzo [ E ] [1,2,4] thiadiazine 1, 1-dioxide derivatives as MRGX2 inhibitors | 索伦特治疗有限责任公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-117964547-A | Urea compound and application thereof as Sigma2 and 5HT2A dual-target inhibitor | 瀚远医药有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2024067304-A1 | COMPOUND WITH INHIBITORY ACTIVITY AGAINST SIGMA2 AND 5HT2A AND USE | 瀚远医药有限公司 | 2024-04-04 | — | — | WO | disclosed |
| US-20240024305-A1 | METHODS AND COMPOSITIONS FOR TREATING RETINA-ASSOCIATED DISEASE USING CCR3-INHIBITORS | ALKAHEST, INC. | 2024-01-25 | — | — | US | disclosed |
| US-20230346764-A1 | Methods and Compositions for Treating Pruritus, Xerosis, and Associated Disease Using CCR3-Inhibitors | ALKAHEST, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230346951-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | YALE UNIVERSITY | 2023-11-02 | — | — | US | disclosed |
| CN-116903767-A | Chelate resin and preparation method and application thereof | 上海稀固科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| US-11787779-B2 | Sulfone pyridine alkyl amide-substituted heteroaryl compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-10-17 | — | — | US | disclosed |
| US-4621090-A | Antifungal compositions | TOYO SODA MANUFACTURING CO., LTD. (JP) | 1986-11-04 | — | — | US | disclosed |
| US-4617307-A | Substituted imidazo[1,5-A]pyridine derivatives as aromatase inhibitors | CIBA-GEIGY CORPORATION (US) | 1986-10-14 | — | — | US | disclosed |
| US-4588732-A | Certain imidazo(1,5-a)pyridine derivatives and their use as thromboxane synthetase inhibitors | CIBA-GEIGY CORPORATION (US) | 1986-05-13 | — | — | US | disclosed |
| EP-0165904-A2 | Substituted bicycle compounds | CIBA-GEIGY AG (CH) | 1985-12-27 | — | — | EP | disclosed |
| EP-0144570-A2 | Antifungal compositions containing carbamates | TOSOH CORPORATION (JP) | 1985-06-19 | — | — | EP | disclosed |
| JP-S6067463-A | PRODUCTION OF THIOCARBAMATE DERIVATIVE | TOYO SODA MFG CO LTD | 1985-04-17 | — | — | JP | disclosed |
| US-4470986-A | ISCHEMIA, SHOCK, THROMBOSIS | CIBA-GEIGY CORPORATION (US) | 1984-09-11 | — | — | US | disclosed |
| EP-0114572-A1 | Substituted imidazo(1,5-a)pyridines | CIBA-GEIGY AG (CH) | 1984-08-01 | — | — | EP | disclosed |
| US-4444775-A | ENZYME INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1984-04-24 | — | — | US | disclosed |